Surgeons battled to save the Liverpool man, but he died yesterday evening. His name was not released by the emergency services.
Paramedic Peter Kent, one of the first men on the scene of the crash near the Huyton turnoff, said the other motorists must have had a "guardian angel" to walk away from the carnage.
He said: "When I looked at the Astra, which was totally wrecked, I couldn't believe that they walked away with just scrapes, bumps and bruises.