Cockroft, who was the first person to set a world record in the stadium earlier this year, got off to a typically explosive start and never looked back.
Only a slight head wind denied her the chance to attack her own world record of 17.60s.
"I've been working for the last four years for that. That was a good race," she told Channel 4.
Asked about her emotions on crossing the line, she said: "I kind of was deciding whether to cry or laugh or what to do. It's a little bit surreal when you've been dreaming about it for so long and then it just kind of happens in, what, 18 seconds?
"You're kind of like, 'I want to do it again. I can do it better.' I've got it now. I can't complain."